Molecular aspects of antibody mediated T cell activation
<p>The normal physiological activation of naive T cells requires the engagement of both the T cell receptor (TCR) and the co-stimulatory molecule, CD28. However, a group of monoclonal antibodies (mAbs) have been identified that are able to activate T cells <em>in vitro</em> and <...
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Format: | Thesis |
Language: | English |
Published: |
2009
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