Molecular aspects of antibody mediated T cell activation

<p>The normal physiological activation of naive T cells requires the engagement of both the T cell receptor (TCR) and the co-stimulatory molecule, CD28. However, a group of monoclonal antibodies (mAbs) have been identified that are able to activate T cells <em>in vitro</em> and <...

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Bibliographic Details
Main Author: Morgan, SH
Other Authors: Davis, S
Format: Thesis
Language:English
Published: 2009
Subjects: