Dynamic combinatorial mass spectrometry for 2-oxoglutarate oxygenase inhibition

<p>In the last decade, dynamic combinatorial mass spectrometry (DCMS) with protein targets has emerged as a promising method for the identification of enzyme-inhibitors. 2-Oxoglutarate (2OG) oxygenases are involved in important biological processes related to many diseases; several human 2OG o...

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Bibliographic Details
Main Author: Demetriades, M
Other Authors: Schofield, C
Format: Thesis
Language:English
Published: 2013
Subjects: