The efficacy of the Quercetin analogue LY294002 in immortalized cancer cell lines is related to the oxygenic and metabolic status of cells

<p><strong>Purpose:</strong> LY294002, a promising drug for chemotherapy, suppresses the activity of Phosphatidylinositol 3-Kinase (PI3K) which is pivotal to a number of processes such as proliferation, metabolism, and apoptosis. The compound has, however, been seen to have very va...

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Bibliographic Details
Main Authors: Huang, X, Potter, M, Pilgrim, B, Ardkhean, R, Kabeshov, M, Claridge, T, Wiseman, M, Morten, K, Donohoe, T, Townley, H
Format: Journal article
Published: International Journal of Cancer Therapy and Oncology 2017