A mutation in the 3' region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverse transcriptase inhibitor resistance.

The Y318F substitution in the 3' region of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) has been linked to nonnucleoside RT inhibitor (NNRTI) resistance in vitro. A systematic search of a large phenotypic-genotypic database (Virco) linked the Y318F substitution with a...

Full description

Bibliographic Details
Main Authors: Harrigan, P, Salim, M, Stammers, D, Wynhoven, B, Brumme, Z, McKenna, P, Larder, B, Kemp, S
Format: Journal article
Language:English
Published: 2002