Direct simulation of the self-assembly of a small DNA origami

By using oxDNA, a coarse-grained nucleotide-level model of DNA, we are able to directly simulate the self-assembly of a small 384-base-pair origami from single-stranded scaffold and staple strands in solution. In general, we see attachment of new staple strands occurring in parallel, but with cooper...

Full description

Bibliographic Details
Main Authors: Snodin, BEK, Romano, F, Rovigatti, L, Ouldridge, TE, Louis, AA, Doye, JPK
Format: Journal article
Language:English
Published: American Chemical Society 2016