Adenovirus VA RNAI blocks ASC oligomerization and inhibits NLRP3 inflammasome activation

Virus infected immune cells can rapidly respond to the invader by activating the inflammasome and as a consequence release proinflammatory cytokines and eventually die by pyroptosis. In human adenovirus-5 (Ad5) infected THP-1 cells, inhibition of NLRP3 inflammasome activation was demonstrated by a d...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Darweesh, M, Kamel, W, Gavrilin, MA, Akusjärvi, G, Svensson, C
বিন্যাস: Journal article
প্রকাশিত: Frontiers Media 2019