The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans.

The ability to digest the milk sugar lactose as an adult (lactase persistence) is a variable genetic trait in human populations. The lactase-persistence phenotype is found at low frequencies in the majority of populations in sub-Saharan Africa that have been tested, but, in some populations, particu...

Full description

Bibliographic Details
Main Authors: Mulcare, C, Weale, M, Jones, A, Connell, B, Zeitlyn, D, Tarekegn, A, Swallow, D, Bradman, N, Thomas, MG
Format: Journal article
Language:English
Published: Cell Press 2004