The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans.
The ability to digest the milk sugar lactose as an adult (lactase persistence) is a variable genetic trait in human populations. The lactase-persistence phenotype is found at low frequencies in the majority of populations in sub-Saharan Africa that have been tested, but, in some populations, particu...
Main Authors: | Mulcare, C, Weale, M, Jones, A, Connell, B, Zeitlyn, D, Tarekegn, A, Swallow, D, Bradman, N, Thomas, MG |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Cell Press
2004
|
Similar Items
-
Four novel mutations in the lactase gene (<it>LCT</it>) underlying congenital lactase deficiency (CLD)
by: Höglund Pia, et al.
Published: (2009-01-01) -
Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population
by: Stefan Németh, et al.
Published: (2022-08-01) -
Ileal Lactase Expression Associates with Lactase Persistence Genotypes
by: Jan Krzysztof Nowak, et al.
Published: (2021-04-01) -
Association of the European lactase persistence variant (LCT-13910 C>T polymorphism) with obesity in the Canary Islands.
by: Ricardo Almon, et al.
Published: (2012-01-01) -
Correction: Several Different Lactase Persistence Associated Alleles and High Diversity of the Lactase Gene in the Admixed Brazilian Population
Published: (2013-01-01)