Glucagon-like peptide 1 stimulates hypothalamic proopiomelanocortin neurons.
Glucagon-like peptide 1 (GLP-1) is a potent inhibitor of food intake. GLP-1 receptor mRNA is densely expressed in hypothalamic arcuate nucleus (ARC) and precisely overlaps the area occupied by proopiomelanocortin (POMC) neurons. Activation of POMC neurons suppresses appetite, and lack of POMC-derive...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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