First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: A meta-analysis of observational studies

BACKGROUND: Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester except in lifesaving circumstances. We conducted a meta-analysis of prospective observational studi...

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Main Authors: Dellicour, S, Sevene, E, McGready, R, Tinto, H, Mosha, D, Manyando, C, Rulisa, S, Desai, M, Ouma, P, Oneko, M, Vala, A, Rupérez, M, Macete, E, Menéndez, C, Nakanabo-Diallo, S, Kazienga, A, Valéa, I, Calip, G, Augusto, O, Genton, B, Njunju, E, Moore, K, d'Alessandro, U, Nosten, F, Ter Kuile, F, Stergachis, A
Format: Journal article
Language:English
Published: Public Library of Science 2017