PRION-1 scales analysis supports use of functional outcome measures in prion disease.

OBJECTIVES: Human prion diseases are heterogeneous but invariably fatal neurodegenerative disorders with no known effective therapy. PRION-1, the largest clinical trial in prion disease to date, showed no effect of the potential therapeutic quinacrine on survival. Although there are several limitati...

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Bibliographic Details
Main Authors: Mead, S, Ranopa, M, Gopalakrishnan, G, Thompson, A, Rudge, P, Wroe, S, Kennedy, A, Hudson, F, MacKay, A, Darbyshire, J, Collinge, J, Walker, A
Format: Journal article
Language:English
Published: 2011