Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.

Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.

It has been suggested that receptor-ligand complexes segregate or co-localise within immune synapses according to their size, and this is important for receptor signaling. Here, we set out to test the importance of receptor-ligand complex dimensions for immune surveillance of target cells by human N...

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Autors principals:	Köhler, K, Xiong, S, Brzostek, J, Mehrabi, M, Eissmann, P, Harrison, A, Cordoba, S, Oddos, S, Miloserdov, V, Gould, K, Burroughs, N, van der Merwe, P, Davis, D
Format:	Journal article
Idioma:	English
Publicat:	Public Library of Science 2010

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