The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding
The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. Thi...
Váldodahkkit: | , , , , , , |
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Materiálatiipa: | Journal article |
Almmustuhtton: |
Nature Publishing Group
2016
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