(-)-Pseudodistomin E: First asymmetric synthesis and absolute configuration assignment

(-)-Pseudodistomin E has been prepared for the first time, allowing its structure and absolute configuration to be confirmed. The established conjugate addition of lithium (S)-N-allyl-N-(α-methyl-p-methoxybenzyl)amide to methyl (E,E)-hepta-2,5-dienoate generated the C(2)-stereocenter, and iodolacton...

Full description

Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Roberts, P, Thomson, J, Zimmer, D
Format: Journal article
Language:English
Published: American Chemical Society 2017