(-)-Pseudodistomin E: First asymmetric synthesis and absolute configuration assignment

(-)-Pseudodistomin E has been prepared for the first time, allowing its structure and absolute configuration to be confirmed. The established conjugate addition of lithium (S)-N-allyl-N-(α-methyl-p-methoxybenzyl)amide to methyl (E,E)-hepta-2,5-dienoate generated the C(2)-stereocenter, and iodolacton...

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Bibliografische gegevens
Hoofdauteurs: Davies, S, Fletcher, A, Roberts, P, Thomson, J, Zimmer, D
Formaat: Journal article
Taal:English
Gepubliceerd in: American Chemical Society 2017