pH-independent sustained release matrix tablet containing doxazosin mesylate: effect of citric acid.

The aim of this study was to develop a pH-independent sustained release matrix tablets of doxazosin mesylate. The matrix tablets were prepared by direct compression technique using polyethylene oxide, sodium alginate and citric acid as a pH modifier. Formulations were evaluated for an in vitro drug...

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Bibliographic Details
Main Authors: Cha, K, Tran, T, Kim, MS, Kim, J, Park, H, Park, J, Cho, W, Hwang, S
Format: Journal article
Language:English
Published: 2010