Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

Apart from surgical approaches, the treatment of cancer remains largely underpinned by radiotherapy and pharmacological agents that cause damage to cellular DNA, which ultimately causes cancer cell death. DNA polymerases, which are involved in the repair of cellular DNA damage, are therefore potenti...

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Bibliographic Details
Main Authors: Parsons, J, Nicolay, N, Sharma, R
Format: Journal article
Language:English
Published: 2013