Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam

To examine transmission dynamics of Mtb isolated from TB patients in Ho Chi Minh City, Vietnam we sequenced whole genomes of 1,635 isolates and compared these with 3,144 isolates from elsewhere. The data reveal an underlying burden of disease caused by endemic Mtb Lineage 1 associated with activatio...

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Main Authors: Holt, K, McAdam, P, Thai, P, Thuong, N, Ha, D, Lan, N, Nhu, N, Hai, H, Ha, V, Thwaites, G, Edwards, D, Nath, A, Pham, K, Ascher, D, Farrar, J, Khor, C, Teo, Y, Inouye, M, Caws, M, Dunstan, S
格式: Journal article
語言:English
出版: Nature Publishing Group 2018