The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis

Background:To investigate small-nucleolar RNAs (snoRNAs) as reference genes when measuring miRNA expression in tumour samples, given emerging evidence for their role in cancer.Methods:Four snoRNAs, commonly used for normalisation, RNU44, RNU48, RNU43 and RNU6B, and miRNA known to be associated with...

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Bibliographic Details
Main Authors: Gee, H, Buffa, F, Camps, C, Ramachandran, A, Leek, R, Taylor, M, Patil, M, Sheldon, H, Betts, G, Homer, J, West, C, Ragoussis, J, Harris, A
Format: Journal article
Language:English
Published: 2011