Calmodulin regulates human ether à go-go 1 (hEAG1) potassium channels through interactions of the Eag domain with the cyclic nucleotide binding homology domain.
The ether à go-go family of voltage-gated potassium channels is structurally distinct. The N terminus contains an eag domain (eagD) that contains a Per-Arnt-Sim (PAS) domain that is preceded by a conserved sequence of 25-27 amino acids known as the PAS-cap. The C terminus contains a region with homo...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2016
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