The role of calnexin, calreticulin and heavy chain glycosylation in MHC class I assembly
<p>Class I heavy chain (HC) must assemble with β-microglobulin (β2m) and acquire optimal peptide in order to be presented to cytotoxic T cells (CTLs). Calnexin is involved in the initial folding of class I HC and subsequent assembly with β2m. Incorporation of "empty" or suboptimally...
Asıl Yazarlar: | , |
---|---|
Diğer Yazarlar: | |
Materyal Türü: | Tez |
Dil: | English |
Baskı/Yayın Bilgisi: |
2002
|
Konular: |