Single-molecule analysis of G protein-coupled receptor stoichiometry: Approaches and limitations

How G protein-coupled receptors (GPCRs) are organized at the cell surface remains highly contentious. Single-molecule (SM) imaging is starting to inform this debate as receptor behavior can now be visualized directly, without the need for interpreting ensemble data. The limited number of SM studies...

Full description

Bibliographic Details
Main Authors: Felce, J, Davis, S, Klenerman, D
Format: Journal article
Language:English
Published: Elsevier 2017