Single-molecule analysis of G protein-coupled receptor stoichiometry: Approaches and limitations

How G protein-coupled receptors (GPCRs) are organized at the cell surface remains highly contentious. Single-molecule (SM) imaging is starting to inform this debate as receptor behavior can now be visualized directly, without the need for interpreting ensemble data. The limited number of SM studies...

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Autori principali: Felce, J, Davis, S, Klenerman, D
Natura: Journal article
Lingua:English
Pubblicazione: Elsevier 2017