A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure

Fibroblast growth factor 21 (FGF21) is a hormone that has insulin-sensitizing properties. Some trials of FGF21 analogs show weight loss and lipid-lowering effects. Recent studies have shown that a common allele in the FGF21 gene alters the balance of macronutrients consumed, but there was little evi...

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Bibliographic Details
Main Authors: Frayling, TM, Beaumont, RN, Jones, SE, Yaghootkar, H, Tuke, MA, Ruth, KS, Casanova, F, West, B, Locke, J, Sharp, S, Ji, Y, Thompson, W, Harrison, J, Etheridge, AS, Gallins, PJ, Jima, D, Wright, F, Zhou, Y, Innocenti, F, Lindgren, CM, Grarup, N, Murray, A, Freathy, RM, Weedon, MN, Tyrrell, J, Wood, AR
Format: Journal article
Language:English
Published: Elsevier 2018