Atropisomeric fragments in drug discovery and probe compound development

<p>This thesis describes work on the use of atropisomeric biaryl compounds in fragment-based drug discovery (FBDD) and probe compound development. </p> <p>Part I describes the investigation of derivatisation methodologies and fragment growth methodologies to generate axially chira...

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Bibliographic Details
Main Author: Danet, B
Other Authors: Brennan, P
Format: Thesis
Language:English
Published: 2022
Subjects: