Adequate sample size for developing prediction models was not simply related to events per variable.
The choice of an adequate sample size for a Cox regression analysis is generally based on the rule of thumb derived from simulation studies (Peduzzi et al. (1995)) of a minimum of 10 events per variable (EPV). One simulation study suggested scenarios in which the 10 EPV rule can be relaxed (Vittingh...
| Autors principals: | , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
Elsevier
2016
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