Active RNA polymerases: mobile or immobile molecular machines?
It is widely assumed that active RNA polymerases track along their templates to produce a transcript. We test this using chromosome conformation capture and human genes switched on rapidly and synchronously by tumour necrosis factor alpha (TNFα); one is 221 kbp SAMD4A, which a polymerase takes more...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Wellcome Trust
2010
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Subjects: |