trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase
Mutants of trt-1, the Caenorhabditis elegans telomerase reverse transcriptase, reproduce normally for several generations but eventually become sterile as a consequence of telomere erosion and end-to-end chromosome fusions. Telomere erosion and uncapping do not cause an increase in apoptosis in the...
Main Authors: | , , , , , , |
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Andre forfattere: | |
Format: | Journal article |
Sprog: | English |
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Public Library of Science
2006
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