Prevention of diabetes but not insulitis in NOD mice injected with antibody to CD4.

Prevention of diabetes but not insulitis in NOD mice injected with antibody to CD4.

Non-obese diabetic (NOD) mice were injected with a rat monoclonal antibody to CD4 from birth every two weeks through 6 months of age. These animals gained weight normally but < 11% of their spleen T cells were CD4+, compared with 28% of CD4+ in controls injected with polyclonal rat IgG. The r...

Bibliografske podrobnosti
Main Authors:	Hayward, A, Shriber, M, Cooke, A, Waldmann, H
Format:	Journal article
Jezik:	English
Izdano:	1993

Podobne knjige/članki

Delay in onset of insulitis in NOD mice following a single injection of CD 4 and CD 8 antibodies.
od: Hayward, A, et al.
Izdano: (1988)

REQUIREMENT FOR CD 4 AND CD 8 T-CELLS FOR TRANSFER OF SIALITIS IN NOD MICE
od: Hayward, A, et al.
Izdano: (1988)

The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice.
od: Hutchings, P, et al.
Izdano: (1992)

Tolerance to IDDM induced by CD4 antibodies in nonobese diabetic mice is reversed by cyclophosphamide.
od: Parish, N, et al.
Izdano: (1993)

The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice
od: Morgan, M, et al.
Izdano: (2013)

Tolerance induction in concordant heart-xenografted mice by CD4 and CD8 monoclonal antibodies.
od: Chen, Z, et al.
Izdano: (1994)

Mapping of an insulin-dependent diabetes locus, Idd9, in NOD mice to chromosome 4.
od: Rodrigues, N, et al.
Izdano: (1994)

Stability of tolerance in mice generated by CD4 and CD8 monoclonal antibody treatment: cell transfer experiments.
od: Chen, Z, et al.
Izdano: (1993)

Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice
od: Mattner, J, et al.
Izdano: (2019)

Class-II and IL2 receptor positive cells in the pancreas of NOD mice.
od: Signore, A, et al.
Izdano: (1987)

Non-invasive multiphoton imaging of islets transplanted Into the pinna of the NOD mouse ear reveals the immediate effect of anti-CD3 treatment in autoimmune diabetes
od: Benson, RA, et al.
Izdano: (2018)

LMP2 expression and proteasome activity in NOD mice.
od: Kessler, B, et al.
Izdano: (2000)

LMP2 expression and proteasome activity in NOD mice
od: Kessler, B, et al.
Izdano: (2000)

TOLERANCE INDUCTION USING CD4 AND CD8 MONOCLONAL-ANTIBODIES
od: Waldmann, H, et al.
Izdano: (1989)

Tolerance induction with CD4 monoclonal antibodies.
od: Waldmann, H, et al.
Izdano: (1998)

Reshaping a therapeutic CD4 antibody.
od: Gorman, S, et al.
Izdano: (1991)

The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice.
od: Signore, A, et al.
Izdano: (1989)

SUPPRESSION OF LOW-DOSE STREPTOZOTOCIN-INDUCED DIABETES IN MICE BY MONOCLONAL-ANTIBODIES TO LYMPHOCYTE-T SUBSETS
od: Kantwerk, G, et al.
Izdano: (1986)

CD4 and CD8 monoclonal antibody therapy in canine renal allografts.
od: Watson, C, et al.
Izdano: (1994)

CD4 monoclonal antibody pairs for immunosuppression and tolerance induction.
od: Qin, S, et al.
Izdano: (1987)

Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies.
od: Cobbold, S, et al.
Izdano: (1992)

Preproinsulin designer antigens excluded from endoplasmic reticulum suppressed diabetes development in nod mice by dna vaccination
od: Stifter, Katja, et al.
Izdano: (2019)

Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8.
od: Cobbold, S, et al.
Izdano: (1996)

Mechanisms of Peripheral Tolerance and Suppression Induced by Monoclonal Antibodies to CD4 and CD8
od: Cobbold, S, et al.
Izdano: (1996)

Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance.
od: Kuhn, C, et al.
Izdano: (2011)

Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes.
od: Hale, G, et al.
Izdano: (2010)

Tolerance induction in the adult using monoclonal antibodies to CD4, CD8, and CD11a (LFA-1).
od: Waldmann, H, et al.
Izdano: (1989)

TOLERANCE INDUCTION IN THE ADULT USING MONOCLONAL-ANTIBODIES TO CD4, CD8, AND CD11A (LFA-1)
od: Waldmann, H, et al.
Izdano: (1989)

Immunosuppression of canine renal allograft recipients by CD4 and CD8 monoclonal antibodies.
od: Watson, C, et al.
Izdano: (1994)

Active suppression induced by anti-CD4.
od: Hutchings, P, et al.
Izdano: (1993)

CD4 and CD8 monoclonal antibody therapy in the dog: strategies to induce tolerance to renal allografts.
od: Watson, C, et al.
Izdano: (1995)

CD4 and CD8 monoclonal antibody therapy: strategies to prolong renal allograft survival in the dog.
od: Watson, C, et al.
Izdano: (1993)

NMDAR antibodies; cognitive and behavioural abnormalities in mice injected with patient IgG
od: Philippa, P, et al.
Izdano: (2010)

Behaviour and neuropathology in mice injected with human contactin- associated protein 2 antibodies
od: Giannoccaro, M, et al.
Izdano: (2019)

CD4 monoclonal antibodies in the preclinical dog renal allograft model.
od: Watson, C, et al.
Izdano: (1993)

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status.
od: Lo, B, et al.
Izdano: (2011)

Suppression in murine experimental autoimmune thyroiditis: in vivo inhibition of CD4+ T cell-mediated resistance by a nondepleting rat CD4 monoclonal antibody.
od: Nabozny, G, et al.
Izdano: (1991)

Resistance to collagen-induced arthritis in DBA/1 mice by intraperitoneal administration of soluble type II collagen involves both CD4+ and CD8+ T lymphocytes.
od: Williams, R, et al.
Izdano: (1989)

Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, and to rat heart xenografts, using monoclonal antibodies to CD4 and CD8.
od: Chen, Z, et al.
Izdano: (1992)

NOD2 REGULATION OF MICRORNAS
od: Brain, O, et al.
Izdano: (2011)