PanGraph: scalable bacterial pan-genome graph construction

The genomic diversity of microbes is commonly parameterized as SNPs relative to a reference genome of a well-characterized, but arbitrary, isolate. However, any reference genome contains only a fraction of the microbial pangenome, the total set of genes observed in a given species. Reference-based a...

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Bibliographic Details
Main Authors: Noll, N, Molari, M, Shaw, LP, Neher, RA
Format: Journal article
Language:English
Published: Microbiology Society 2023