Inherited variability of tumor necrosis factor production and susceptibility to infectious disease.
Tumor necrosis factor (TNF) is a critical mediator of host defense against infection but may cause severe pathology when produced in excess. Individuals vary in the amount of TNF produced when their peripheral blood mononuclear cells are stimulated in vitro, and family studies indicate that much of...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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