Structural insights into Notch receptor-ligand interactions

Pioneering cell aggregation experiments from the Artavanis-Tsakonas group in the late 1980's localized the core ligand recognition sequence in the Drosophila Notch receptor to epidermal growth factor-like (EGF) domains 11 and 12. Since then, advances in protein expression, structure determinati...

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Bibliographic Details
Main Authors: Handford, PA, Korona, B, Suckling, R, Redfield, C, Lea, SM
Format: Book section
Language:English
Published: Springer, Cham 2018