Cyclic AMP promotes the survival of dopaminergic neurons in vitro and protects them from the toxic effects of MPP+.
We have studied how stimulation of protein kinase C and cAMP-dependent protein kinases affect the development of mesencephalic dopaminergic neurons in vitro. IGF-I and bFGF did not activate either second messenger system nor affect the survival of dopaminergic neurons but stimulated dopamine uptake...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1995
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