Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis.
BACKGROUND: Inflammation and matrix degradation are the hallmarks of high-risk atherosclerosis that leads to myocardial infarction and stroke. Toll-like receptors (TLRs), key players in innate immunity, are upregulated in atherosclerotic lesions, but their functional role in human atherosclerosis i...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2009
|