Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis.

BACKGROUND: Inflammation and matrix degradation are the hallmarks of high-risk atherosclerosis that leads to myocardial infarction and stroke. Toll-like receptors (TLRs), key players in innate immunity, are upregulated in atherosclerotic lesions, but their functional role in human atherosclerosis i...

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Bibliographic Details
Main Authors: Monaco, C, Gregan, S, Navin, T, Foxwell, B, Davies, A, Feldmann, M
Format: Journal article
Language:English
Published: 2009