Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis.
BACKGROUND: Inflammation and matrix degradation are the hallmarks of high-risk atherosclerosis that leads to myocardial infarction and stroke. Toll-like receptors (TLRs), key players in innate immunity, are upregulated in atherosclerotic lesions, but their functional role in human atherosclerosis i...
Main Authors: | Monaco, C, Gregan, S, Navin, T, Foxwell, B, Davies, A, Feldmann, M |
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Format: | Journal article |
Language: | English |
Published: |
2009
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