AN INVESTIGATION INTO THE MECHANISM OF ELASTASE INHIBITION BY CEPHALOSPORINS USING ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY
Electrospray ionisation mass spectrometry was used to investigate the mechanism of inhibition of porcine pancreatic elastase (PPE) by two cephalosporins, L-658758 [1-[[3-(acetoxymethyl)-7α-metyoxy-8-oxo-5-thia-1-azabicyclo[4.2.0.]oct-2-en-2-yl]carbonyl]proline S,S dioxide], and L-647957 [1-[[3-(acet...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
1993
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