Primaquine induced haemolysis in G6PD heterozygous females treated for the radical cure of Plasmodium vivax malaria: a nested cohort study

Background<br/> Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females are mosaics who, because of X-chromosome inactivation (Lyo...

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Main Authors: Chu, C, Bancone, G, Moore, K, Win, H, Thitipanawan, N, Po, C, Chowwiwat, N, Raksapraidee, R, Wilairisak, P, Phyo, A, Keereecharoen, L, Proux, S, Charunwatthana, P, Nosten, F, White, N
Format: Journal article
Published: Public Library of Science 2017