Measuring internal forces in single-stranded DNA: application to a DNA force clamp

We present a new method for calculating internal forces in DNA structures using coarse-grained models and demonstrate its utility with the oxDNA model. The instantaneous forces on individual nucleotides are explored and related to model potentials, and using our framework, internal forces are calcul...

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Bibliographic Details
Main Authors: Engel, MC, Romano, F, Louis, AA, Doye, JPK
Format: Journal article
Language:English
Published: American Chemical Society 2020