Determination of anti-acetylcholine receptor antibodies in myasthenic patients by use of time-resolved fluorescence.

BACKGROUND: Autoantibodies against nicotinic acetylcholine receptor (nAChR) in myasthenia gravis (MG) patients are usually detected by radioimmunoprecipitation assays using extracted acetylcholine receptors labeled irreversibly with 125I-alpha-bungarotoxin (alpha-BuTx). To provide a nonradioactive...

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Bibliographic Details
Main Authors: Rícný, J, Simková, L, Vincent, A
Format: Journal article
Language:English
Published: 2002