A functional human IgM response to HIV-1 Env after immunization with NYVAC HIV C.

Env-specific IgG and IgM were detected in 25 and 60%, respectively, of volunteers immunized with NYVAC expressing clade C gp120. The serum sample with the highest IgM titre but undetectable IgG neutralized the homologous isolate with a reciprocal IC90 titre of 7.8 in the absence of complement, and 2...

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Bibliografiske detaljer
Main Authors: Sheppard, N, Bates, A, Sattentau, Q
Format: Journal article
Sprog:English
Udgivet: 2007