A functional human IgM response to HIV-1 Env after immunization with NYVAC HIV C.
Env-specific IgG and IgM were detected in 25 and 60%, respectively, of volunteers immunized with NYVAC expressing clade C gp120. The serum sample with the highest IgM titre but undetectable IgG neutralized the homologous isolate with a reciprocal IC90 titre of 7.8 in the absence of complement, and 2...
Main Authors: | Sheppard, N, Bates, A, Sattentau, Q |
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格式: | Journal article |
語言: | English |
出版: |
2007
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