Tryptophan 2,3-dioxygenase expression identified in murine decidual stromal cells is not essential for feto-maternal tolerance

Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) catalyze the rate-limiting step of tryptophan catabolism along the kynurenine pathway, which has important immuno suppressive properties, particularly in tumor cells and dendritic cells. The prominent expression of IDO1 in the...

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Үндсэн зохиолчид: Hoffmann, D, Dvorakova, T, Schramme, F, Stroobant, V, Van den Eynde, BJ
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Frontiers Media 2020