Transcriptional modulation of human endogenous retroviruses in primary CD4+ T xells following vorinostat treatment

Transcriptional modulation of human endogenous retroviruses in primary CD4+ T xells following vorinostat treatment

The greatest obstacle to a cure for HIV is the provirus that integrates into the genome of the infected cell and persists despite antiretroviral therapy. A “shock and kill” approach has been proposed as a strategy for an HIV cure whereby drugs and compounds referred to as latency-reversing agents (L...

书目详细资料
Main Authors:	White, C, Beliakova-Bethell, N, Lada, S, Breen, M, Hurst, T, Spina, C, Richman, D, Frater, J, Magiorkinis, G, Woelk, C
格式:	Journal article
语言:	English
出版:	Frontiers Research Foundation 2018

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