Acute cytomegalovirus infection is associated with increased frequencies of activated and apoptosis-vulnerable T cells in HIV-1-infected infants.

Cytomegalovirus (CMV) coinfection is associated with infant HIV-1 disease progression and mortality. In a cohort of Kenyan HIV-infected infants, the frequencies of activated (CD38(+) HLA-DR(+)) and apoptosis-vulnerable (CD95(+) Bcl-2(-)) CD4(+) and CD8(+) T cells increased substantially during acute...

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Bibliographic Details
Main Authors: Slyker, J, Rowland-Jones, S, Dong, T, Reilly, M, Richardson, B, Emery, VC, Atzberger, A, Mbori-Ngacha, D, Lohman-Payne, B, John-Stewart, G
Format: Journal article
Language:English
Published: 2012