Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges
Background: Since the discovery that indoleamine 2,3-dioxygenase (IDO) is a modulator for maintenance of fetomaternal immuno-privilege state, it has been implicated in tumour tolerance, autoimmune diseases and asthma. IDO is an IFN-γ-inducible, intracellular enzyme that catalyzes the initial and rat...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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