Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges

Background: Since the discovery that indoleamine 2,3-dioxygenase (IDO) is a modulator for maintenance of fetomaternal immuno-privilege state, it has been implicated in tumour tolerance, autoimmune diseases and asthma. IDO is an IFN-γ-inducible, intracellular enzyme that catalyzes the initial and rat...

詳細記述

書誌詳細
主要な著者: Quan, J, Tan, P, MacDonald, A, Friend, P
フォーマット: Journal article
言語:English
出版事項: 2008