Substrate selectivity and inhibition of histidine JmjC hydroxylases MINA53 and NO66.

<p>Non-haem Fe(II) and 2-oxoglutarate (2OG) dependent oxygenases catalyse oxidation of multiple proteins in organisms ranging from bacteria to humans. We describe studies on the substrate selectivity and inhibition of the human ribosomal oxygenases (ROX) MINA53 and NO66, members of the JmjC 2O...

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Bibliographic Details
Main Authors: Türkmen, VA, Hintzen, JCJ, Tumber, A, Moesgaard, L, Salah, E, Kongsted, J, Schofield, CJ, Mecinović, J
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2023