Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families.

Míreanna comhchosúla

• Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk
  de réir: Rees, MG, et al.
  Foilsithe / Cruthaithe: (2011)
• Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk.
  de réir: Rees, MG, et al.
  Foilsithe / Cruthaithe: (2012)
• Functional analysis of GCKR mutations identified in subjects with hypertriglyceridaemia demonstrates the inherent challenges in clinical interpretation of rare variants
  de réir: Raimondo, A, et al.
  Foilsithe / Cruthaithe: (2012)
• The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
  de réir: Beer, N, et al.
  Foilsithe / Cruthaithe: (2009)
• A panel of diverse assays to interrogate the interaction between glucokinase and glucokinase regulatory protein, two vital proteins in human disease
  de réir: Rees, MG, et al.
  Foilsithe / Cruthaithe: (2014)