Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.

In peripheral tissues, corticosteroid hormone action is determined, in part, through the activity of 11beta-hydroxysteroid dehydrogenases (11beta-HSD), two isozymes of which interconvert hormonally active cortisol (F) and inactive cortisone (E). 11beta-HSD type 2 (11beta-HSD2) inactivates F to E in...

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Bibliographic Details
Main Authors: Stewart, P, Toogood, A, Tomlinson, J
Format: Journal article
Language:English
Published: 2001