A new multipoint method for genome-wide association studies by imputation of genotypes.

Genome-wide association studies are set to become the method of choice for uncovering the genetic basis of human diseases. A central challenge in this area is the development of powerful multipoint methods that can detect causal variants that have not been directly genotyped. We propose a coherent a...

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Detalles Bibliográficos
Main Authors: Marchini, J, Howie, B, Myers, S, McVean, G, Donnelly, P
Formato: Journal article
Idioma:English
Publicado: 2007