Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil

<strong>Introduction</strong> Synapse loss is the structural correlate of the cognitive decline indicative of dementia. In the brains of Alzheimer's disease sufferers, amyloid β (Aβ) peptides aggregate to form senile plaques but as soluble peptides are toxic to synapses. We previous...

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Bibliographic Details
Main Authors:	Sellers, K, Elliott, C, Jackson, J, Ghosh, A, Ribe, E, Rojo, A, Jarosz-Griffiths, H, Watson, I, Xia, W, Semenov, M, Morin, P, Hooper, N, Porter, R, Preston, J, Al-Shawi, R, Baillie, G, Lovestone, S, Cuadrado, A, Harte, M, Simons, P, Srivastava, D, Killick, R
Format:	Journal article
Language:	English
Published:	Elsevier 2017

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil

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